|
|
Registro Completo |
Biblioteca(s): |
Embrapa Meio Ambiente. |
Data corrente: |
05/04/2021 |
Data da última atualização: |
05/04/2021 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
MEDEIROS, A. M. Z.; KHAN, L. U.; SILVA, G. H. da; OSPINA, C. A.; ALVES, O. L.; CASTRO, V. L. S. S. de; MARTINEZ, D. S. T. |
Afiliação: |
ALINE MARIA ZIGIOTTO DE MEDEIROS, CNPEM; LATIF ULLAH KHAN, CNPEM; GABRIELA HELENA DA SILVA, CNPEM; CARLOS ALBERTO OSPINA, CNPEM; OSWALDO LUIZ ALVES, IQ-UNICAMP; VERA LUCIA SCHERHOLZ S DE CASTRO, CNPMA; DIEGO STÉFANI TEODORO MARTINEZ, CNPEM. |
Título: |
Graphene oxide-silver nanoparticle hybrid material: an integrated nanosafety study in zebrafish embryos. |
Ano de publicação: |
2021 |
Fonte/Imprenta: |
Ecotoxicology and Environmental Safety, v. 209, article 111776, 2021. |
ISSN: |
0147-6513 |
DOI: |
https://doi.org/10.1016/j.ecoenv.2020.111776 |
Idioma: |
Inglês |
Conteúdo: |
Abstract: This work reports an integrated nanosafety study including the synthesis and characterization of the graphene oxide-silver nanoparticle hybrid material (GO-AgNPs) and its nano-ecotoxicity evaluation in the zebrafish embryo model. The influences of natural organic matter (NOM) and a chorion embryo membrane were considered in this study, looking towards more environmentally realistic scenarios and standardized nanotoxicity testing. The nanohybrid was successfully synthesized using the NaBH4 aqueous method, and AgNPs (~ 5.8 nm) were evenly distributed over the GO surface. GO-AgNPs showed a dose-response acute toxicity: the LC50 was 1.5 mg L-1 for chorionated embryos. The removal of chorion, however, increased this toxic effect by 50%. Furthermore, the presence of NOM mitigated mortality, and LC50 for GO-AgNPs changed respectively from 2.3 to 1.2 mg L-1 for chorionated and de-chorionated embryos. Raman spectroscopy confirmed the ingestion of GO by embryos; but without displaying acute toxicity up to 100 mg L-1, indicating that the silver drove toxicity down. Additionally, it was observed that silver nanoparticle dissolution has a minimal effect on these observed toxicity results. Finally, understanding the influence of chorion membranes and NOM is a critical step towards the standardization of testing for zebrafish embryo toxicity in safety assessments and regulatory issues. |
Palavras-Chave: |
Alternative methods; Grafeno; Nanoecotoxicology; Nanohybrids; Nanomateriais; Nanotoxicity. |
Thesagro: |
Composto de Carbono; Peixe de Água Doce; Toxidez. |
Thesaurus Nal: |
chorion; Danio rerio; Ecotoxicology; Graphene oxide; Nanomaterials. |
Categoria do assunto: |
P Recursos Naturais, Ciências Ambientais e da Terra |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/222338/1/Castro-Graphene-oxide-2021.pdf
|
Marc: |
LEADER 02533naa a2200385 a 4500 001 2131052 005 2021-04-05 008 2021 bl uuuu u00u1 u #d 022 $a0147-6513 024 7 $ahttps://doi.org/10.1016/j.ecoenv.2020.111776$2DOI 100 1 $aMEDEIROS, A. M. Z. 245 $aGraphene oxide-silver nanoparticle hybrid material$ban integrated nanosafety study in zebrafish embryos.$h[electronic resource] 260 $c2021 520 $aAbstract: This work reports an integrated nanosafety study including the synthesis and characterization of the graphene oxide-silver nanoparticle hybrid material (GO-AgNPs) and its nano-ecotoxicity evaluation in the zebrafish embryo model. The influences of natural organic matter (NOM) and a chorion embryo membrane were considered in this study, looking towards more environmentally realistic scenarios and standardized nanotoxicity testing. The nanohybrid was successfully synthesized using the NaBH4 aqueous method, and AgNPs (~ 5.8 nm) were evenly distributed over the GO surface. GO-AgNPs showed a dose-response acute toxicity: the LC50 was 1.5 mg L-1 for chorionated embryos. The removal of chorion, however, increased this toxic effect by 50%. Furthermore, the presence of NOM mitigated mortality, and LC50 for GO-AgNPs changed respectively from 2.3 to 1.2 mg L-1 for chorionated and de-chorionated embryos. Raman spectroscopy confirmed the ingestion of GO by embryos; but without displaying acute toxicity up to 100 mg L-1, indicating that the silver drove toxicity down. Additionally, it was observed that silver nanoparticle dissolution has a minimal effect on these observed toxicity results. Finally, understanding the influence of chorion membranes and NOM is a critical step towards the standardization of testing for zebrafish embryo toxicity in safety assessments and regulatory issues. 650 $achorion 650 $aDanio rerio 650 $aEcotoxicology 650 $aGraphene oxide 650 $aNanomaterials 650 $aComposto de Carbono 650 $aPeixe de Água Doce 650 $aToxidez 653 $aAlternative methods 653 $aGrafeno 653 $aNanoecotoxicology 653 $aNanohybrids 653 $aNanomateriais 653 $aNanotoxicity 700 1 $aKHAN, L. U. 700 1 $aSILVA, G. H. da 700 1 $aOSPINA, C. A. 700 1 $aALVES, O. L. 700 1 $aCASTRO, V. L. S. S. de 700 1 $aMARTINEZ, D. S. T. 773 $tEcotoxicology and Environmental Safety$gv. 209, article 111776, 2021.
Download
Esconder MarcMostrar Marc Completo |
Registro original: |
Embrapa Meio Ambiente (CNPMA) |
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
Registro Completo
Biblioteca(s): |
Embrapa Agroindústria de Alimentos. |
Data corrente: |
03/02/2011 |
Data da última atualização: |
03/02/2011 |
Tipo da produção científica: |
Resumo em Anais de Congresso |
Autoria: |
OLIVEIRA, E. M. M.; OLIVEIRA, T. C. de; LIMA, I. S. de; FERREIRA, T. |
Afiliação: |
EDNA MARIA MORAIS OLIVEIRA, CTAA; TATIANE CORREA DE OLIVEIRA, CTAA; IVANILDA SANTOS DE LIMA, UERJ; THIAGO FERREIRA, UNIG. |
Título: |
Detecção e quantificação de soja geneticamente modificada em rações para diferentes animais. |
Ano de publicação: |
2010 |
Fonte/Imprenta: |
In: CONGRESSO BRASILEIRO DE CIÊNCIA E TECNOLOGIA DE ALIMENTOS, 22., 2010, Salvador. Potencialidades, desafios e inovações. [S.l.]: SBCTA, 2010. 1 CD-ROM. |
Idioma: |
Português |
Palavras-Chave: |
OGM; PCR em tempo real; Rotulagem de alimentos. |
Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/26367/1/2010-119.pdf
|
Marc: |
LEADER 00639nam a2200169 a 4500 001 1875661 005 2011-02-03 008 2010 bl uuuu u00u1 u #d 100 1 $aOLIVEIRA, E. M. M. 245 $aDetecção e quantificação de soja geneticamente modificada em rações para diferentes animais. 260 $aIn: CONGRESSO BRASILEIRO DE CIÊNCIA E TECNOLOGIA DE ALIMENTOS, 22., 2010, Salvador. Potencialidades, desafios e inovações. [S.l.]: SBCTA, 2010. 1 CD-ROM.$c2010 653 $aOGM 653 $aPCR em tempo real 653 $aRotulagem de alimentos 700 1 $aOLIVEIRA, T. C. de 700 1 $aLIMA, I. S. de 700 1 $aFERREIRA, T.
Download
Esconder MarcMostrar Marc Completo |
Registro original: |
Embrapa Agroindústria de Alimentos (CTAA) |
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
Nenhum registro encontrado para a expressão de busca informada. |
|
|